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    题名: The epidemiology and progression time from transient to permanent psychiatric disorders of substance-induced psychosis in Taiwan
    作者: Che, Wei-Ling;Chen, Wei-Ling;謝佳宏;Hsieh, Chia-Hung;Cha, Hao-Teng;Chang, Hao-Teng;Hu, Chia-Chun;Hung, Chia-Chun;Ch, Chin-Hong;Chan, Chin-Hong
    贡献者: 生物與醫學資訊學系
    日期: 2015-02
    上传时间: 2015-05-05 06:31:55 (UTC+0)
    摘要: Introduction

    Substance-induced psychosis (SIP), including alcohol-induced psychotic disorder (AIPD) and substance-induced psychotic disorder (SIPD), is gradually increasing in importance in clinical practice. However, few studies have investigated the epidemiology and progression time from transient to permanent psychiatric disorders for AIPD and SIPD patients.

    Methods

    We utilized the National Health Insurance Research Database (NHIRD) to investigate the incidence and prevalence of AIPD and SIPD in Taiwan and determined the timing of AIPD or SIPD followed by the development of persistent psychotic conditions.

    Results

    The average incidence and prevalence were 1.97 and 2.94 per 100,000 person-years for AIPD, 3.09 and 5.67 per 100,000 person-years for SIPD in Taiwan. Moreover, 10.9% to 24.3% of subjects with either AIPD or SIPD had a change in diagnosis to either schizophrenia or affective disorder, and ~ 50% of patients had a psychotic or affective transformation in their first year after AIPD and SIPD diagnoses. The mean progression time of psychotic or affective transformation was 1.9 to 2.7 years.

    Conclusions

    SIP is a predictive factor for persistent psychotic and affective transformation, and a three-year follow-up may be an optimal clinical practice to prevent psychotic or affective transformation in 60% of patients.
    關聯: ADDICTIVE BEHAVIORS
    显示于类别:[生物資訊與醫學工程學系 ] 期刊論文

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