The potential therapeutic applications of olfactory ensheathing cells in regenerative medicine

ASIAIR > College of Medical and Health Science > Department of Biotechnology > Journal Article > Item 310904400/86942

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Title:	The potential therapeutic applications of olfactory ensheathing cells in regenerative medicine
Authors:	Chou, Ruey-Hwang;Lu, Cheng-You;Wei-Lee;Fan, Jia-Rong;Yu, Yung-Luen;Shyu, Woei-Cherng
Contributors:	生物科技學系
Keywords:	Neuronal injury;Olfactory ensheathing cells (OECs);Regenerative medicine
Date:	2014-04
Issue Date:	2014-11-07 06:54:35 (UTC+0)
Abstract:	Olfactory ensheathing cells (OECs) are unique glia cells restricted to the primary olfactory system including the olfactory mucosa, olfactory nerve, and the outer nerve layer of the olfactory bulb. OECs guide growing olfactory axons from the neurons of the nasal cavity olfactory mucosa to the olfactory bulb to connect both the peripheral nervous system (PNS) and central nervous system (CNS). Based on these specialized abilities of OECs, transplantation of OECs to injury sites has been widely investigated for their potential therapeutic applications in neural repair in different injuries. In this article, we reviewed the properties of OECs and their roles in olfactory regeneration and in treatment of different injuries including spinal cord injury, PNS injury, and stroke and neurodegenerative diseases.
Relation:	CELL TRANSPLANTATION,23(4-5),567-571.
Appears in Collections:	[Department of Biotechnology] Journal Article

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