SYNDROMES, DISORDERS AND MATERNAL RISK FACTORS ASSOCIATED WITH NEURAL TUBE DEFECTS (IV)

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題名:	SYNDROMES, DISORDERS AND MATERNAL RISK FACTORS ASSOCIATED WITH NEURAL TUBE DEFECTS (IV)
作者:	Chen, CP (Chen, Chih-Ping)
貢獻者:	Department of Biotechnology
關鍵詞:	fetal;maternal;neural tube defects;risk factors； FOLIC-ACID FORTIFICATION;REDUCED FOLATE CARRIER;DIHYDROFOLATE-REDUCTASE DHFR;IN-VITRO FERTILIZATION;THYMIDYLATE SYNTHASE GENE;DEHYDROGENASE-METHENYLTETRAHYDROFOLATE-CYCLOHYDROLASE;PERICONCEPTIONAL VITAMIN SUPPLEMENTATION;SPINA-BIFIDA PREGNANCY;MAJOR BIRTH-DEFECTS;METHYLENETETRAHYDROFOLATE REDUCTASE
日期:	2008-06
上傳時間:	2010-03-26 02:29:42 (UTC+0)
出版者:	Asia University
摘要:	Fetuses with neural tube defects (NTDs) may be associated with maternal and fetal risk factors. This article provides a comprehensive review of maternal and fetal risk factors associated with NTDs, such as infertility, periconceptional clomiphene use and assisted reproductive technology, periconceptional folic acid deficiency and effects of folic acid supplementation and fortification on NTD rates, periconceptional vitamin B12 deficiency, single nucleotide polymorphisms and polymorphisms in genes of folate metabolism, and maternal autoantibodies to folate receptors. NTDs associated with maternal and fetal risk factors are an important cause of NTDs. Perinatal identification of NTDs should alert the clinician to the maternal and fetal risk factors associated with NTDs, and prompt a thorough etiologic investigation and genetic counseling.
關聯:	TAIWANESE JOURNAL OF OBSTETRICS & GYNECOLOGY 47 (2): 141-150
顯示於類別:	[生物科技學系] 期刊論文

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