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| Title: | Polyethylene terephthalate/chitosan tubular knits made by using a freeze-drying method |
| Authors: | 林佳弘;Lin, Jia-Horng;Li, Mei-Hui;Li, Mei-Hui;We, Shih-Peng;Wen, Shih-Peng;Lo, Ching Wen;Lou, Ching Wen |
| Contributors: | 時尚設計學系 |
| Date: | 2014-03 |
| Issue Date: | 2014-06-05 03:21:43 (UTC+0) |
| Abstract: | Biomaterials are commonly used in vitro or in vivo. Synthetic vascular prostheses, artificial bones, and artificial joints are used in vitro. Bone scaffolds demand components with good biocompatibility, mechanical strengths, and pore size. This allows the bone tissue to attach to and grow inside the bone scaffolds. Polyethylene terephthalate (PET) filaments and chitosan have good biocompatibility and are non-toxic. This study prepares biocompatible, porous, 1- and 2-layer three-dimensional PET/chitosan tubular knits by a freeze-drying method. PET plied yarns with three combinations of various denier (D) and coefficients of twist-150D/2, 225D/4, and 300D/3-are knitted into tubular knits with proper mechanical properties and porous structure. The resulting tubular knits are then alkali treated with 3 M sodium hydroxide (NaOH) reagent for 90 min, immersed in 1 wt% chitosan solution, and then freeze-dried, forming the porous PET/chitosan tubular knits. The functional group analysis and degradation of the alkali-treated chitosan films are first evaluated, and then the tensile strength, surface observation, pore size, and biocompatibility of the resulting PET/chitosan tubular knits are evaluated. The experimental result shows that 1- and 2-layer PET/chitosan tubular knits have desirable mechanical strength, stability, and biocompatibility antibacterial properties. |
| Relation: | TEXTILE RESEARCH JOURNAL |
| Appears in Collections: | [時尚設計學系] 期刊論文
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