Modular Structures and Robustness of Protein Networks

ASIA unversity > 資訊學院 > 生物資訊與醫學工程學系 > 期刊論文 > Item 310904400/4770

jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://asiair.asia.edu.tw/ir/handle/310904400/4770

题名:	Modular Structures and Robustness of Protein Networks
作者:	Jeffrey J. P. Tsai;K.L. Ng;C.H. Huang;P.H. Lee;J.F. Fang
关键词:	Protein-protein interaction;random graphs;scale-free networks;hierarchical networks;network robustness
日期:	2006-04
上传时间:	2009-12-02 01:04:07 (UTC+0)
出版者:	Asia University
摘要:	The topological structures and robustness of the protein-protein interaction networks (PINs) is studied via random graph theory. Several global topological parameters are used to characterize PINs for seven species. Good evidence by correlation analysis support the fact that the seven PINs are well approximated by scale-free networks. It is also found that two of the species' PINs are well described by the hierarchical models. In particular, it is determined that the E. coli and the yeast PINs are well represented by the stochastic and deterministic hierarchical network models respectively. These results suggest that the hierarchical network model is a better description for certain species' PINs. Furthermore, it is demonstrated that PINs are robust with respective to failure, attack, random rewiring and edge deletion perturbations.
關聯:	International Journal of Artificial Intelligence Tools 15(2):309-321
显示于类别:	[生物資訊與醫學工程學系 ] 期刊論文

文件中的档案:

档案	描述	大小	格式	浏览次数
		0Kb	Unknown	511	检视/开启
310904400-4770.doc		35Kb	Microsoft Word	231	检视/开启

在ASIAIR中所有的数据项都受到原著作权保护.