This paper aims to explore the impact of interpersonal network, personality?department culture and job performance on job satisfaction. A group of workers from a company of tire industry are surveyed. This study uses ?Social Network Analysis? and Ucinet 6.212 to compute the network degree and network betweenness of all respondents. Respondents who get higher personal network degree will be much more closer to network central. Those who get higher network betweenness will be much more capable to play a ?local bridge? role. In addition, the SPSS 12.0 software is used to perform various statistics analyses. The main research findings are as follows: 1. The network degree and network betweenness of interpersonal network have no effects on job satisfaction. 2. Extraversion personality has a positive effect on job satisfaction: In the extrinsic satisfaction and intrinsic satisfaction, extraversion personality has a positive effect on job satisfaction; however it has effect on general satisfaction. 3. Job performance has a positive effect on extrinsic satisfaction and intrinsic satisfaction; however, no effects are found in general satisfaction. 4. Department culture does not have any moderating effect on job satisfaction.