This study was discussed the different parts of Corchorus capsularis, and their antioxidant activity and the ability on the inflammatory effects by LPS-activated macrophage cell line. In the antioxidant activity, CGLEE had the best suppression. In transient transfection assay showed that the CVHWE activated PPAR? significantly. The MTT assay results showed that Corchorus capsularis extracts treatments did not significantly influence the cell viability. However, the Corchorus capsularis leaf reject vein hot water extract (CLRVHWE) had no effect. The CCLEE could inhibited the PGE2 synthesis, and Corchorus capsularis hot water extract had no significantly difference. In addition, suppression on LPS-induced COX-2 protein expression of RAW264.7 showed that CGLEE was the best. The CLCVHWE and CLRVHWE inhibited COX-2 protein expression, but PGE2 had no different with vehicle. In the NF-?B p65 protein expression, the CSME and CLCVHWE had significant ability inhibition. In conclusion, the effects of CGLEE could suppressed NO2, PGE2 and COX-2 protein expression and decreased NF-?B p65 protein expression.
