Analysis of Regulatory Element Clusters in Human Promoter Regions

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题名:	Analysis of Regulatory Element Clusters in Human Promoter Regions
作者:	Lin Jun Gu
贡献者:	Department of Bioinformatics
关键词:	bioinformatics;promoter;regulatory protein;prediction;linear regression
日期:	2004
上传时间:	2009-11-06 14:31:27 (UTC+0)
出版者:	Asia University
摘要:	As a result of the Human Genome Project, people can utilize the whole genome sequence of human. We can use the information of DNA or protein sequence to analyze the function of genes. In general, the structure of gene can separate to several parts. We are interesting to the promoter of the gene. This paper provides a method that can predict the location of promoter in the DNA sequence. Basing the weighted matrix of regulatory protein binding sites, and the formula of liner regression, we try to predict the position of promoter of human DNA sequence and to analyze the proximity of promoter, such as the position of core promoter, regulatory protein binding site and transcription mechanism model. We hope this method can abbreviate the preparing time of biological experiments and provide more information about promoter when biologists prepare the biological experiment.
显示于类别:	[生物資訊與醫學工程學系 ] 博碩士論文

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