Pars plana vitrectomy for diabetic fibrovascular proliferation with and without internal limiting membrane peeling.

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Title:	Pars plana vitrectomy for diabetic fibrovascular proliferation with and without internal limiting membrane peeling.
Authors:	PY), (Chang;CM)*, (Yang;CH), (Yang;MS), (Chen;Wang), 王俊毅(Jiun-Yi
Contributors:	健康產業管理學系
Keywords:	diabetic retinopathy;epiretinal membrane;fibrovascular proliferation;internal membrane peeling
Date:	2009-04
Issue Date:	2012-11-26 04:06:02 (UTC+0)
Abstract:	"ObjectiveTo evaluate the anatomical and functional results of internal limiting membrane (ILM) peeling during pars plana vitrectomy for fibrovascular proliferation (FVP) in diabetic retinopathy.MethodsThe study was a prospective comparative case series in design. Patients undergoing pars plana vitrectomy for mild to moderate diabetic FVP were divided into either Group 1: vitrectomy only, or Group 2: further ILM peeling in the macular area. Best-corrected visual acuity, fundus examination, and optical coherence tomography (OCT) were conducted at 3 and 6 months postoperatively.ResultsThere were 26 eyes of 25 patients in Group 1 (non-ILM peeling) and 23 eyes of 22 patients in Group 2 (ILM peeling). At 6 months postoperatively, OCT-identifiable epiretinal membrane (ERM) was found in 10 of 26 eyes (38.5%) in Group 1and 0 of 23 eyes in Group 2 (P=0.001) and six eyes (23.1%) in Group 1 developed biomicroscopic ERM, whereas no patients in Group 2 had ERM (P=0.02) at 6 months. OCT identifiable ERM correlated significantly with central macular thickness (r=−0.58, P<0.001), the presence of intraretinal cystic space (r=0.60, P<0.001), and fovea depression reappearance (r=0.36, P=0.008). Factors associated with poor visual outcome were macular detachment (P<0.001) and non-ILM peeling (P=0.004).ConclusionsThis pilot study suggests that ILM peeling during vitrectomy for diabetic fibrovascular proliferative membranes may minimize postoperative ERM formation and improve visual prognosis.Eye (2009) 23, 960–965; doi:10.1038/eye.2008.334; published online 7 November 2008[ABSTRACT FROM AUTHOR] Copyright of Eye is the property of Nature Publishing Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.Copyright applies to all Abstracts."
Relation:	EYE
Appears in Collections:	[健康產業管理學系] 期刊論文

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