ASIA unversity:Item 310904400/17774
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    题名: Microalbuminuria and the metabolic syndrome and its components in the Chinese population
    作者: Chang-Sheng Sheng;Bang-Chuan Hu;Wang-Xiang Fan;Jun Zou;Yan Li;Ji-Guang Wang
    贡献者: 健康產業管理學系
    日期: 2007
    上传时间: 2012-11-26 04:03:26 (UTC+0)
    摘要: Background
    We investigated the prevalence of microalbuminuria and its association with the metabolic syndrome and its components in a Chinese population.

    Methods
    The study subjects were recruited from a newly established residential area in the suburb of Shanghai. We measured anthropometry, blood pressure (BP), fasting plasma glucose, and serum lipids, and collected spot urine samples for the determination of albumin-creatinine ratio. We defined microalbuminuria as a urinary albumin-to-creatinine ratio of 30 to 299 mg/g. The metabolic syndrome was defined according to the International Diabetes Federation criteria.

    Results
    The 1079 participants included 410 (38.0%) hypertensive patients, and 66 (6.1%) diabetic patients. The prevalence of microalbuminuria (4.3%) was 3.2 times higher in 167 patients with the metabolic syndrome than 912 subjects without the metabolic syndrome (12.0% vs. 2.9%, P < 0.0001). In multiple regression adjusted for sex, age, body mass index, current smoking, alcohol intake and the use of antihypertensive drugs, and mutually adjusted for the components, microalbuminuria was significantly associated with diastolic BP (odds ratio 1.74 for +10 mmHg; 95% confidence interval [CI] 1.10-2.76; P = 0.02) and fasting plasma glucose (1.18; 95% CI 1.01-1.41; P = 0.04), but not with waist circumference, systolic BP, or serum HDL cholesterol and triglycerides (P > 0.10).

    Conclusions
    Microalbuminuria is common in the Chinese population, and much more prevalent in the presence of the metabolic syndrome, mainly attributable to elevated diastolic BP and plasma glucose.
    關聯: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION,3:6.
    显示于类别:[健康產業管理學系] 期刊論文

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