ASIA unversity:Item 310904400/16487
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    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/16487


    Title: Pd2(dba)3-promoted synthesis of 3-substituted 4-aryl-1,2,3,6-tetrahydropyridine
    Authors: 張清堯;Chang, Ching-Yao
    Contributors: 生物科技學系
    Keywords: N-Bromosuccinimide;4-Aryl-1,2,3,6-tetrahydropyridine;Cross coupling;JohnPhos
    Date: 2010-09
    Issue Date: 2012-11-23 09:13:45 (UTC+0)
    Abstract: "A novel method for the synthesis of 3-N-substituted 4-aryl-1,2,3,6-tetrahydropyridine 3 is presented. The process is carried out by the allylic bromination of 4-aryl-1,2,3,6-tetrahydropyridines 1 with N-bromosuccinimide in propanoic acid and palladium-catalyzed cross coupling of the corresponding bromide 2 with different N-based nucleophiles.
    Relation: TETRAHEDRON LETTERS
    Appears in Collections:[Department of Biotechnology] Journal Article

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