Low-density lipoprotein (LDL) apheresis reduces atherogenic and oxidative markers in uremic patients with hyperlipidemia

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Title:	Low-density lipoprotein (LDL) apheresis reduces atherogenic and oxidative markers in uremic patients with hyperlipidemia
Authors:	;Chen, Tung-Sheng;Liou, Show-Yih;Wu, Hsi-Chin;Tsai, Fuu-Jen;Tsai, Chang-Hai;黃志揚;HUANG, CHIH-YANG;Chang, Yen-Lin
Contributors:	生物科技學系
Keywords:	Atherosclerosis;Hemodialysis;Hyperlipidemia;LDL apheresis;Oxidative stress;Uremic patients
Date:	2010-02
Issue Date:	2012-11-23 09:12:31 (UTC+0)
Abstract:	"Uremic patients with hyperlipidemia are classiﬁed at high atherogenic risk due to oxidative stress induced by regular hemodialysis process (hemoincompatibility) and a high level of oxidized low-density lipoprotein (ox-LDL). This study aimed to investigate whether LDL apheresis was capable of reducing oxidative and atherogenic markers in uremic patients with hyperlipidemia. We found that oxidative metabolites (methylquanidine, dityrosine, and ox-LDL) and atherogenic markers (lipoprotein (a), LDL, and LDL/HDL ratio) were signiﬁcantly reduced (P\0.05) after LDL apheresis. On the other hand, plasma total antioxidant status (TAS) was no"
Relation:	International Urology and Nephrology
Appears in Collections:	[Department of Biotechnology] Journal Article

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