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http://asiair.asia.edu.tw/ir/handle/310904400/115452
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| Title: | Secondary metabolites with Antimicrobial activities from Chamaecyparis obtusa var. formosana |
| Authors: | Wu, Ming-Der;Wu, Ming-Der;Che, Ming-Jen;Cheng, Ming-Jen;Che, Jih-Jung;Chen, Jih-Jung;Nanthaphong;Khamthong, Nanthaphong;Lin, Wen-Wei;Lin, Wen-Wei;郭悅雄;Kuo, Yueh-Hsiung |
| Contributors: | 醫學暨健康學院醫學檢驗暨生物技術學系 |
| Keywords: | Chamaecyparis obtusa var. formosana, Cupressaceae, novel skeleton, dimer, diterpenoid, traditional herbal medicine, antimicrobial activities |
| Date: | 2022-01-01 |
| Issue Date: | 2023-03-29 02:23:58 (UTC+0) |
| Publisher: | 亞洲大學 |
| Abstract: | Seven new compounds, including one dimer novel skeleton, chamaecyformosanin A (1); three diterpenes, chamaecyformosanins B–D (2–4); one sesquiterpene, chamaecyformosanin E (5); and two monoterpenes, chamaecyformosanins F and G (6 and 7) were isolated from the methanol extract of the bark of Chamaecyparis obtusa var. formosana. Their structures were established by the mean of spectroscopic analysis and the comparison of NMR data with those of known analogues. Their structures were elucidated on the basis of physicochemical evidence, in-depth NMR spectroscopic analysis, and high-resolution mass spectrometry. Furthermore, the isolated compounds were subjected to an evaluation of their antimicrobial activity. Metabolites 1, 3, and 4 present antibacterial activities. It is worth mentioning that the chemical composition of the bark of C. obtusa var. formosana has never been studied in the past. This is the first time the barks from C. obtusa var. formosana were studied and two new skeleton compounds, 1 and 7, were obtained. |
| Appears in Collections: | [生物科技學系] 期刊論文
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