Novel Antifungal Dimers from the Roots of Taiwania cryptomerioides

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题名:	Novel Antifungal Dimers from the Roots of Taiwania cryptomerioides
作者:	Che, Ming-Jen;Cheng, Ming-Jen;Wu, Ming-Der;Wu, Ming-Der;Cha, Chao-Lin;Chang, Chao-Lin;Ch, Hsun-Shuo;Chang, Hsun-Shuo;Chiou-Fung, Chiou-Fung C;Chyu, Chiou-Fung;郭悅雄;Kuo, Yueh-Hsiung
贡献者:	醫學暨健康學院醫學檢驗暨生物技術學系
关键词:	Taiwania cryptomerioides;Taxodiaceae;novel skeleton;dimer;diterpenoid;antifungal activities
日期:	2022-01-01
上传时间:	2023-03-29 02:23:27 (UTC+0)
出版者:	亞洲大學
摘要:	Five new dimer compounds, namely Taiwaniacryptodimers A–E (1–5), were isolated from the methanol extract of the roots of Taiwania cryptomerioides. Their structures were established by mean of spectroscopic analysis and comparison of NMR data with those of known analogues. Their antifungal activities were also evaluated. Our results indicated that metabolites 1, 2, 4, and 5 displayed moderate antifungal activities against Aspergillus niger, Penicillium italicum, Candida albicans, and Saccharomyces cerevisiae.
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