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    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/115148


    Title: Association between Pre-Existing Sleep Disorders and Survival Rates of Patients with Breast Cancer
    Authors: Ch, Yen-Chang;Chen, Yen-Chang;Che, Wan-Ming;Chen, Wan-Ming;Ch, Ming-Feng;Chiang, Ming-Feng;Sh, Ben-Chang;Shia, Ben-Chang;吳思遠;Wu, Szu-Yuan
    Contributors: 醫學暨健康學院食品營養與保健生技學系
    Keywords: breast cancer;invasive ductal carcinoma;risk factor;sleep disorder;survival.
    Date: 2022-02-01
    Issue Date: 2023-03-29
    Publisher: 亞洲大學
    Abstract: Purpose: To investigate the effects of pre-existing sleep disorders on the survival outcomes of women receiving standard treatments for breast invasive ductal carcinoma (IDC).

    Methods: We recruited patients from the Taiwan Cancer Registry Database who had received surgery for clinical stage I-III breast IDC. The Cox proportional hazards model was used to analyze all-cause mortality. We categorized the patients into those with and without sleep disorders (Groups 1 and 2, respectively) through propensity score matching.

    Results: In the multivariate Cox regression analysis, the adjusted hazard ratio for all-cause mortality for Group 1 compared with Group 2 was 1.51 (95% confidence interval: 1.19, 1.91; p < 0.001).

    Conclusion: Our study demonstrated that the sleep disorder group had poorer survival rates than the non-sleep disorder group in breast cancer. Therefore, patients should be screened and evaluated for pre-existing sleep disorders prior to breast surgery, with such disorders serving as a predictor of survival in patients with breast cancer. Future studies may investigate the survival benefits of pharmacological and behavioral treatments for sleep problems in patients with breast cancer.
    Appears in Collections:[Department of Food Nutrition and Healthy Biotechnology] Journal Article

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