The majority of colon and rectal cancers arise from previously benign adenoma through the adenoma-carcinoma sequence. Discrimination between neoplastic and nonneoplastic lesions is crucial to avoid overtreatment of nonneoplastic lesions. Narrow band imaging (NBI) is a new-developed optical chromoendoscopy to highlight microvascular structure upon mucosa surface without inconvenience of dye spraying used in conventional chromoendoscopy. Both conventional chromoendoscopy and NBI need magnifying colonoscopy to achieve high diagnostic accuracy, but magnifying colonoscopy are not routinely used in clinical practice. We analyze numerical data of red, green, blue components under white light (WL) and NBI in 36 polyps. Significant difference between two lesions is demonstrated in features including standard deviation (SD), Kurt, Entropy, and Energy for each components under WL and NBI except SD and Kurt on red component under NBI. The more homogeneous mucosa surface in hyperplasia polyp contributes to the presentation. The mean on green component under NBI also achieve significant difference that may result from less absorption over the larger pit area in adenomatous polyp. Accuracy of computer-aided diagnostic performance is higher by NBI than by WL that is compatible with previous investigations under clinical research without computer-aided analysis.
