以臺灣腦中風登錄資料庫分析臺灣地區中風與腦中風急性期藥物治療選擇之關聯性探討

ASIA unversity > 資訊學院 > 生物資訊與醫學工程學系 > 博碩士論文 > Item 310904400/112146

Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/112146

Title:	以臺灣腦中風登錄資料庫分析臺灣地區中風與腦中風急性期藥物治療選擇之關聯性探討 Analysis of the Association between Stroke and Acute Treatment of Stroke in Patients with Stroke in Taiwan Using Taiwan Brain Stroke Registry
Authors:	張凱喜 Chang, Kai-His
Contributors:	生物資訊與醫學工程學系碩士在職專班
Keywords:	高血壓;高血脂;心肌梗塞;喝酒;抽菸;心臟病;肥胖;頸動脈循環狹窄;糖尿病 hypertension;hyperlipidemia;diabetes;heart disease;smoking;alcoholism;obesity;carotid stenosis;myocardial infarction
Date:	2019
Issue Date:	2019-10-22 01:40:38 (UTC+0)
Publisher:	亞洲大學
Abstract:	背景與目的 —本研究評估臺灣腦中風登錄資料庫分析梗塞性腦中風藥物治療及選擇是造成腦中風病患死亡率與罹病率增加的最主要因素。研究方法 —比較 2016 至 2019 年期間因急性缺血中風入院而接受藥物治療，探討分析住院治療死亡率及存活率，資料來源為腦中風登錄資料庫，共6206位初次梗塞性腦中風病患的病歷紀錄，分別運用雙樣本獨立t檢定、卡方檢定方法進行資料分析。研究結果 —本研究之死亡率較高病人平均年齡為67.97歲，且以男性稍多，約佔61.55%；施用治療藥物阿斯匹靈、肝素及法華林三種藥物和治療方式動脈內血栓移除手術(血栓溶解)、呼吸器及留置鼻胃管對於缺血性腦中風病患來說，與病患之死亡風險呈現正相關的關係，是減低死亡風險的重要因素；共存性疾病如泌尿道感染、不施予心肺復甦術、復健、吞嚥困難、重返加護病房及動過手術等為缺血性腦中風病患死亡風險較高的相關因素。結論 —急性缺血性腦中風病人急診治療方式分析出，施用阿斯匹靈、靜脈注射血栓溶解劑治療或是動脈內血栓移除手術後有明顯神經功能恢復，對急性腦梗塞結果顯示有效且安全。本研究結果能提供醫護人員未來在臨床上評估梗塞性腦中風病人病程進展之參考。 Background and Purpose: This study used Taiwan Stroke Registry System to analyze if choosing of infarction stroke was the main factor for increasing mortality and morbidity of stroke patients. Research Method: The study discussed mortality and survivability of hospitalization in accepting medication for acute ischemic stroke between 2016 and 2019 in comparison. The data was the medical records of 6206 first-time infarction stroke patients from Taiwan Stroke Registry System. It was analyzed by two-sample independent t test and chi-square test separately. Result: The average age of patients of higher mortality in this study was 67.97 years old. Males were more than females, accounted for 61.55%. For the patients of ischemic stroke, taking the medication, such as aspirin, heparin and warfarin, and also trying the treatment, for example, IA (intra-arterial) thrombectomy (thrombolysis), breathing apparatus and indwelling nasogastric tube showed positive association with mortality risk of the patients. It was the important factor for reducing mortality risk. Co-existing diseases, for instance, urinary tract infection, DNR (do not resuscitate), rehabilitation, dysphagia, readmission to intensive care units, and undergone a surgery were the related factors of higher mortality risk for ischemic stroke patients. Conclusion: Analyzed from the emergency treatment of acute ischemic stroke patients, there was a significant neurological recovery after taking aspirin, intravenous thrombolytic therapy (rt-PA), or IA thrombectomy. It was effective and safe for curing acute infarction stroke. The result of the study could provide the reference for medical staff to evaluate clinically the disease progress of infarction stroke patients in the future.
Appears in Collections:	[生物資訊與醫學工程學系 ] 博碩士論文

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