We aimed to investigate and compare the effects of electrical stimulation and intermittent compressive forces on soft tissue mechanical properties. Four healthy individuals were recruited into this study. A transcutaneous electrical stimulation device was used to apply a pulse duration of 2.5 ms, a frequency of 2 Hz, and the amplitude to a maximum of 30 mA. The intermittent compressive forces were applied at a period of 20 s with forces ranging from 0 to 70 mmHg. The effective Young’s modulus was calculated to characterize mechanical properties of forearm soft tissues. The results showed that forearm soft tissue properties might decrease effective Young’s modulus after the treatments of electrical stimulation and intermittent compressive forces. We aimed to investigate and compare the effects of electrical stimulation and intermittent compressive forces on soft tissue mechanical properties. Four healthy individuals were recruited into this study. A transcutaneous electrical stimulation device was used to apply a pulse duration of 2.5 ms, a frequency of 2 Hz, and the amplitude to a maximum of 30 mA. The intermittent compressive forces were applied at a period of 20 s with forces ranging from 0 to 70 mmHg. The effective Young’s modulus was calculated to characterize mechanical properties of forearm soft tissues. The results showed that forearm soft tissue properties might decrease effective Young’s modulus after the treatments of electrical stimulation and intermittent compressive forces.