Evaluating clinical risk factors for suicide attempts in patients with epilepsy

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题名:	Evaluating clinical risk factors for suicide attempts in patients with epilepsy
作者:	Harnod, Tomor;Harnod, Tomor;Lin, Cheng-Li;Lin, Cheng-Li;高嘉鴻;Kao, Chia-Hung;*
贡献者:	生物資訊與醫學工程學系
日期:	2018-01
上传时间:	2018-08-20 01:45:12 (UTC+0)
摘要:	Abstract Objective We would like to exam whether epilepsy patients in Taiwan have a high risk of attempted and completed suicide. Methods In this study, we used a subset of the National Health Insurance Research Database (NHIRD) of Taiwan. Inpatients (≥ 18 years) who received a new diagnosis of epilepsy between 2000 and 2011 were enrolled in the epilepsy cohort. The epilepsy and comparison cohorts included 68,543 patients and 2-fold controls respectively. We calculated the adjusted hazard ratio (aHR) for suicide attempts after adjustment for age, sex, monthly income, the urbanization level, occupation, and comorbidity. Results The epilepsy cohort had a 2.06-fold risk of suicide attempts (95% CI = 1.65–2.56) compared with the control cohort. The suicide attempt risk did not significantly differ between men and women and between patients with and without psychiatric comorbidity. The mortality risk after a suicide attempt was higher in the epilepsy cohort than in the comparison cohort (aHR = 1.66, 95% CI = 1.02–2.69). Conclusion Epilepsy is an independent and predisposing factor for suicide attempt. These results provide important information for clinicians and governments to prevent suicide in epilepsy patients in Asian countries.
關聯:	JOURNAL OF AFFECTIVE DISORDERS
显示于类别:	[生物資訊與醫學工程學系 ] 期刊論文

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