Identification of Cancer Genes － A Comparison of t-test and SAM

ASIA unversity > 資訊學院 > 生物資訊與醫學工程學系 > 博碩士論文 > Item 310904400/10922

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题名:	Identification of Cancer Genes － A Comparison of t-test and SAM
作者:	Che-Hau Chang
贡献者:	Department of Bioinformatics
关键词:	Significance Analysis of Microarrays, t-test;tumor suppressor genes, oncogenes;liver cancer, esophaguae cancer, breast cancer
日期:	2010
上传时间:	2010-11-08 02:33:16 (UTC+0)
出版者:	Asia University
摘要:	This research aims at comparing the performance of two approaches in predicting cancer genes, i.e oncogenes (OCG), tumor suppressor genes (TSG) and cancer-related genes (others), for three different types of cancers, namely, liver cancer, esophaguae cancer and breast cancer. Gene expression data are downloaded from EBI ArrayExpress. The student t-test approach and the Significance Analysis of Microarrays (SAM) are employed to identify cancer genes. It is found that t-test performs better for esophagaue caner and breast cancer, while SAM performs better for liver cancer. The web site of studying results is available at http://ppi.bioinfo.asia.edu.tw/P_Cancer_T_SAM/
显示于类别:	[生物資訊與醫學工程學系 ] 博碩士論文

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