ASIA unversity:Item 310904400/108419
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    题名: A case of para-Bombay phenotype caused by homozygous mutation of FUT1 gene
    作者: 余志強;ER TZE KIONG
    贡献者: 保健營養生技學系
    日期: 2017-12
    上传时间: 2017-12-08 06:11:58 (UTC+0)
    摘要: A 79-year-old female patient presented at the hospital with
    osteoarthritis. Examination of the patient revealed hemoglobin
    level of 10.8 g/dL, RBC count of 3.45x106
    /µL, WBC count of
    10.1x103/µL, and platelet count of 122x103
    /µL. Plasma levels of
    blood urea nitrogen, creatinine, sodium, potassium, and alanine
    aminotransferase were all within the normal ranges, while
    aspartate aminotransferase was slightly higher than normal. A
    blood sample obtained from the patient was submitted to our
    division for blood typing and cross-matching, with a request
    to receive 2 units of packed red blood cells. ABO typing was
    performed using standard serological techniques after an
    immediate spin. Testing the patient’s red blood cells revealed no
    detectable ABO antigens upon forward/cell grouping (group O
    blood type). On the other hand, reverse/serum grouping showed
    the presence of A antibodies in the serum (group B blood type).
    To resolve the discrepancy between cell and serum grouping we
    performed an agglutination examination of anti-H serum; the
    red blood cells from the sample did not exhibit an agglutination
    reaction. Additionally, secretor status was determined in order
    to assess the presence of soluble blood group substances.
    Our results showed the presence of B and H antigens in the
    saliva. Based on these results, the patient in the present case
    was diagnosed as having a para-Bombay B phenotype (Table 1,
    Figure 1).
    關聯: Turkish Journal of Hematology
    显示于类别:[食品營養與保健生技學系] 期刊論文

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