Chemopreventive effect of natural dietary compounds on xenobiotic-induced toxicity

ASIA unversity > 醫學暨健康學院 > 食品營養與保健生技學系 > 期刊論文 > Item 310904400/108405

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题名:	Chemopreventive effect of natural dietary compounds on xenobiotic-induced toxicity
作者:	Wu, Jia-Ching
贡献者:	保健營養生技學系
日期:	2017
上传时间:	2017-12-08 06:11:02 (UTC+0)
摘要:	Contaminants (or pollutants) that affect human health have become an important issue, spawning a myriad of studies on how to prevent harmful contaminant-induced effects. Recently, a variety of biological functions of natural dietary compounds derived from consumed foods and plants have been demonstrated in a number of studies. Natural dietary compounds exhibited several beneficial effects for the prevention of disease and the inhibition of chemically-induced carcinogenesis. Contaminant-induced toxicity and carcinogenesis are mostly attributed to the mutagenic activity of reactive metabolites and the disruption of normal biological functions. Therefore, the metabolic regulation of hazardous chemicals is key to reducing contaminant-induced adverse health effects. Moreover, promoting contaminant excretion from the body through Phase I and II metabolizing enzymes is also a useful strategy for reducing contaminant-induced toxicity. This review focuses on summarizing the natural dietary compounds derived from common dietary foods and plants and their possible mechanisms of action in the prevention/suppression of contaminant-induced toxicity.
關聯:	JOURNAL OF FOOD AND DRUG ANALYSIS
显示于类别:	[食品營養與保健生技學系] 期刊論文

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