A Relevance Research on Patients’ Medication Adherence and Heart In-Stent Restenosis

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题名:	A Relevance Research on Patients’ Medication Adherence and Heart In-Stent Restenosis
作者:	WU, HUI-CHUN
贡献者:	生物資訊與醫學工程學系碩士在職專班
关键词:	Medication Adherence;Stents;Restenosis;Cardiovascular Disease;National Health Insurance Research Database(NHIRD)
日期:	2017
上传时间:	2017-02-23 02:00:48 (UTC+0)
出版者:	亞洲大學
摘要:	As the development of advanced technology and the enhancement of life quality, the population of people suffering from cardiovascular disease is rising due to unhealthy dietary habits and scarcity of doing exercise. Stent implantation which can make patients recover rapidly has already become one of the main treatment. After the treatment, patients need to follow doctor’s prescription to take the medicine correctly to prevent restenosis. However, the highly researchable NHIRD can inspect patients’ medical history. As a result, the purpose of the study is to verify the relevance of patients’ medication adherence and heart in-stent restenosis. This study adopts patients who have implanted one stent based on Bare Metal Stent(BMS) or Drug Eluting Stent(DES) from 2008 to 2011 as the sample and then tracks their dual medication possession ratio(MPR) as their medication adherence. Using appropriate statistical analysis investigates restenosis between BMS and DES. Finally, analyze the relations between restenosis and patients’ medication adherence on using BMS or DES. It turns out that the percentage of heart in-stent restenosis on using DES is lower than using BMS and patients’ medication adherence on using BMS or DES has no correlations with heart in-stent restenosis. This study also shows other results from two different stent types and patients’ medication adherence on using BMS or DES. First, on two different stent types: 1.More men than women have implanted heart stents and the median of patients’ age are 67 and 64 on BMS and DES. 2.The risk of smoking and the alcohol intake is increasing on patients using BMS; while patients using DES have higher risk of suffering from hyperlipidemia and obesity. 3.Most BMS patients live in central Taiwan and the area of lower urbanization. Their comorbidity is higher on account of lower socioeconomic status; while most DES patients live in north Taiwan and the area of higher urbanization. Their comorbidity is lower on account of higher socioeconomic status. Second, on patients’ medication adherence on using BMS or DES: 1.From selected BMS patients who can be tracked more than six months and use dual anti-platelet agents(DAPT), there was no correlation between medication adherence and restenosis of patients using BMS. 2.From selected DES patients who can be tracked more than one year and use dual anti-platelet agents(DAPT), there was no correlation between medication adherence and restenosis of patients using DES.
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