Utility of overnight pulse oximeter as a screening tool for sleep apnea to assess the 8-year risk of cardiovascular disease: Data from a large-scale bus driver cohort study

ASIA unversity > 醫學暨健康學院 > 健康產業管理學系 > 期刊論文 > Item 310904400/101745

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Title:	Utility of overnight pulse oximeter as a screening tool for sleep apnea to assess the 8-year risk of cardiovascular disease: Data from a large-scale bus driver cohort study
Authors:	Wu, Wei-Te;Wu, Wei-Te;*;Tsai, Su-Shan;Tsai, Su-Shan;Lin, Yu-Jen;Lin, Yu-Jen;Li, Ming-Hsiu;Lin, Ming-Hsiu;吳聰能;Wu, Trong-Neng;Tung-Sheng, Sheng S;Shih, Tung-Sheng;Saou-Hsing, L;Liou, Saou-Hsing
Contributors:	健康產業管理學系
Date:	2016-09
Issue Date:	2016-11-08 02:31:56 (UTC+0)
Abstract:	Background Professional drivers' work under conditions predisposes them for development of sleep-disordered breathing (SDB) and cardiovascular disease (CVD). However, the effect of SDB on CVD risk among professional drivers has never been investigated. A cohort study was used to evaluate the effectiveness of overnight pulse oximeter as a sleep apnea screening tool to assess the 8-year risk of CVD events. Methods The Taiwan Bus Driver Cohort Study (TBDCS) recruited 1014 professional drivers in Taiwan since 2005. The subjects completed questionnaire interview and overnight pulse oximeter survey. This cohort was linked to the National Health Insurance Research Dataset (NHIRD). Researchers found 192 CVD cases from 2005 to 2012. Cox proportional hazards model was performed to estimate the hazard ratio for CVD. The statistical analysis was performed using SAS software in 2015. Results ODI4 and ODI3 levels increased the 8-year CVD risk, even adjusting for CVD risk factors (HR: 1.36, 95% CI: 1.05 to 1.78; p = 0.022, and HR: 1.40, 95% CI: 1.03 to 1.90; p = 0.033). ODI4 and ODI3 thresholds of 6.5 and 10 events/h revealed differences of CVD risks (HR: 1.72, 95% CI: 1.00 to 2.95; p = 0.048, and HR: 1.76, 95% CI: 1.03 to 3.03; p = 0.041). Moreover, the ODI levels had an increased risk for hypertensive disease (not including essential hypertension). Conclusions This study concludes that ODI for a sign of SDB is an independent predictor of elevated risk of CVD. Further research should be conducted regarding measures to prevent against SDB in order to reduce CVD risk in professional drivers.
Relation:	INTERNATIONAL JOURNAL OF CARDIOLOGY
Appears in Collections:	[健康產業管理學系] 期刊論文

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