English  |  正體中文  |  简体中文  |  Items with full text/Total items : 94286/110023 (86%)
Visitors : 21655706      Online Users : 216
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
Scope Tips:
  • please add "double quotation mark" for query phrases to get precise results
  • please goto advance search for comprehansive author search
    •  Adv. Search
    Home ‧ Login ‧ Upload ‧ Help ‧ About ‧ Administer Goto mobile version


    Please use this identifier to cite or link to this item: http://asiair.asia.edu.tw/ir/handle/310904400/100837


    Title: The Incidence of Anemia among Patients with Schizophrenia in Taiwan
    Authors: Chang, Kai-Hui
    Contributors: 健康產業管理學系健康管理組碩士在職專班
    Keywords: Folate deficiency;Vitamin B12;Iron deficiency anemia;Anemia;Schizophrenia;Taiwan
    Date: 2016
    Issue Date: 2016-08-16 07:50:45 (UTC+0)
    Publisher: 亞洲大學
    Abstract: Background: Many haematological disorders may be encountered in psychiatric practice. These include deficiencies in various constituents—leucopenia, neutropenia, agranulocytosis, thrombocytopenia, altered platelet function. However, in epidemiology rarely examined the incidence of anemia with psychiatric illness by population-based study. The aim of this study was to compare the incidence and relative risk of anemia among with Schizophrenia and non-psychiatric patients in Taiwan.
    Materials and Methods: This was a retrospective cohort study. By using the National Health Insurance Database (LHID2000) from 2000 to 2010, children and adolescents older than 15 years old with a new diagnosis of Schizophrenia disorders were identified, excluding anemia diseases and related likely impact of anemia-related diseases. At last, we selected with Schizophrenia who pick up more than two times over-prescription of psychiatric illness or taking antipsychotics amount is more than 7DDD and compared with age, gender-match controls (1:3) in an investigation of the increased risk of anemia. All subjects are traced to 2010, using Multivariable Cox’s proportional hazards model to estimate the risk of anemia morbidity and 95% confidence intervals. Data processing and statistical analyses were performed with Statistical Analysis Software (SAS) version 9.4, survival curve were performed with Statistical Package for Social Science (SPSS) version 18.
    Results: A total of 1092 patients with Schizophrenia disorders and 3276 persons without psychiatric disorders were included. The anemia incidence rate was 43.38 per 1000 person-years among with Schizophrenia disorders and 36.01 per 1000 person-years among non-psychiatric disorders. Hazard rate of anemia among patients with Schizophrenia was statistical significant higher hazard rate (crude HR=1.21, 95% CI 1.05-1.39) than non-psychiatric patients. After controlling other all influence factors, compared with non-psychiatric comparison group, adjusted hazard rate of anemia among patients with schizophrenia was 1.13 (95% CI 0.94-1.37). After using Log-rank test to measure the cumulative incidence in survival curves of the two groups of anemia, the results still show groups of Schizophrenia of anemia cumulative incidence rate was higher (p = 0.008).
    Conclusion: Compared with non-psychiatric comparison group, patients with Schizophrenia disorders did have a higher risk of anemia. It recommends that we need further studies in the future to clarify the mechanism of association between anemia and psychiatric illnesses.
    Appears in Collections:[長期照護組] 博碩士論文

    Files in This Item:

    File Description SizeFormat
    index.html0KbHTML286View/Open


    View Licence

    All items in ASIAIR are protected by copyright, with all rights reserved.

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - Feedback